| June 8 "First Time I Met the Blues"
Route 66 Road House
- Blues In the Schools Roundup: Songs for 2006 Vicksburg Blues, St. James Infirmary, and John Henry
- Centennial Celebrations: Little Brother Montgomery (Barrelhouse Chuck), Roosevelt Sykes (Don Washington, Julien Brunetaud), Blind Arvella Grey (Cary Baker)
Mississippi Juke Joint
- Mississippi Round Robin: Lonnie Gearshifter Youngblood, Terry Harmonica Bean, and Ben Wiley Payton
- Delta Blues Museum Educational Program
U.S. Cellular Front Porch
- Blues in the Schools: Stone Academy, Drummond School and Reavis School
- Fernando Jones and the Chicago Blues Ensemble
- Saffire: the Uppity Blues Woman
Louisiana Bayou Station and Social Club
Gibson Guitar Cross Roads
- The Lost Treasures of the Blues
- Charlie Love and the Silky Smooth with Special Guests Osee Anderson, John Hill, Liz Mandville Greeson, Delores Scott and Mr. Mean
Petrillo Music Shell
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June 9 "Drivin' Wheel"
Route 66 Roadhouse
- Songwriting: Johnnie Mae Dunson Smith
Mississippi Juke Joint
- Mississippi Round Robin Part 2 featuring Gearshifter, Harmonica Bean, and Ben Wiley Payton
- Smokey Smothers and Elvin Bishop
U.S. Cellular Front Porch
Louisiana Bayou Station and Social Club
- Henry Butler with Vasti Jackson
Gibson Guitar Cross Roads
- Duwayne Burnside and the Mississippi Mafia
Petrillo Music Shell
- Henry Butler Band w/ Vasti Jackson
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June 10 "Wang Dang Doodle"
Route 66 Roadhouse
- The Blues Congress: The Not-for -Profit Representation in the Preservation of the Blues
- Howlin' Wolf Birthday Party
Mississippi Juke Joint
- Master Set: Honey boy Edwards, Robert Jr., Homesick James, and Henry Townsend.
- Harmonica Jam Station: featuring Harper and the spirit of Little Walter Lee Boys
U.S. Cellular Front Porch
- Master Set: David "Honeyboy" Edwards, Robert Jr. Lockwood, Henry Townsend and Homesick James
- Zydeco Joe , The Jack Rabbit
Louisiana Bayou Station and Social Club
Gibson Guitar Cross Roads
Petrillo Music Shell
- Eddie Shaw and the Wolf Gang with Special Guests Mary Lane, Henry Gray and Abb Locke
- Siegel-Schwall Blues Band w/ Marcy Levy
- Walter Wolfman Washington and the Roadmasters
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June 11 "St. James Infirmary"
Route 66 Roadhouse
- The Role of the Biography in the perpetuation of the Legacy of the Blues or how Blues Literature spreads the word.
- Chicago Blues, Today with David Whiteis
Mississippi Juke Joint
- Dancin' Perkins w/ Smilin' Bobby and their sons
U.S. Cellular Front Porch
Louisiana Bayou Station and Social Club
- Blues:Chicago's Global Muse A Silk Road Experiment Between John Primer, Yoko Noge, Tatsu Aoki, Hide Yoshihashi, Amy Homma, Avreeayl Ra (drums) and Taiko Drums.
Gibson Guitar Cross Roads
- Nolan Struck and King Edward with Jackie Bell
Petrillo Music Shell
- Next Generation Soul Blues showcasing Vick Allen, the PG Man with Lady Audrey, and Omar Cunningham featuring the Platinum Band
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